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3-MMC, synthetic cannabinoids, 2C-B... these new synthetic drugs that are available online

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They are called "new synthetic drugs", but they are not so new anymore. They were developed to look like the most famous drugs (MDMA, LSD), but their effects are sometimes much more treacherous. Overview

Drugs work like just about any commodity in the capitalist world. First there is the novelty effect, then the prices go down, they find an audience (or if you prefer, a market), until they get bored and new products arrive, finding a new public, creating a new market.

For a long time, however, the possibilities were limited. The number of "mainstream" drugs was limited (cocaine, ecstasy for example), and natural molecules (hallucinogenic mushrooms, cannabis, etc.) were not suitable for everyone. But that has changed: today, production methods have evolved, and it is quite simple to invent new molecules. These are called "new synthetic products" (NPS) or "new synthetic drugs" (NDS)('New Psychoactive Substances', NSP, originally meant new substances that were not yet classified as drugs, but the terms are sometimes confused today). These drugs correspond, according to the definition of the Interministerial Mission for the Fight against Drugs and Addictive Behaviours, to new "synthetic substances, infinitely modifiable and potentially innumerable", developed to resemble known drugs with a similar molecular structure. . In fact, their effects are often much more powerful, and their level of addiction higher, than their predecessors. But as they are almost infinitely declinable, as soon as one of them is prohibited, another appears and circumvents the legislation.

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At the same time, new distribution methods (deliverymen, sales directly on the internet, dark web) have also been deployed . The combination of the two made possible the arrival of these new drugs, which reached a much larger audience.

Today there are hundreds of different new synthetic products, grouped into 8 families (cathinones, synthetic cannabinoids, synthetic opioids (including fentanyloids), phenetylamines (psychedelics or not), tryptamines, piperazines , synthetic benzodiazepines, and arylcyclohexylamines/arylakylamines), but cannabinoids and cathinones (see below) account for the bulk of seizures . Here are the main products found on the market today.

On the same subject ⋙ Report: I hunted new synthetic drugs with French customs officers

Mephedrone

Family : cathinones

Mephedrone, invented in the 1930s, is part of the cathinone family, ie drugs similar to khat, a psychotropic plant that grows in East Africa. It experienced a comeback in the late 2000s and developed in the West before being banned in France in 2010. It was particularly popular in clubbing and gay circles. It is known to lead to a rather difficult descent and, like most cathinones, has a very highly addictive potential.

Other names : 4-MMC, M-cat, mephe, meow meow, bath salts

Effects : Mephedrone is both empathogenic (it facilitates contact) and euphoric. As such, its effects are described as oscillating between those of MDMA (the active ingredient of ecstasy) and amphetamines (which are also found in ecstasy), which are more exciting.

3-MMC

Family : cathinones

Derived from mephedrone, 3-MMC (and its big sister 4-MEC) is a new synthetic drug (NDS), and all three (3-MMC, 4-MMC or mephedrone and 4-MEC) have effects quite close. It appeared in 2011, a year after the ban on 4-MMC in France, and is highly addictive.

Other names : mophedrone

Effects : 3-MMC is psychostimulant and entactogenic (or empathogenic, ie it encourages contact and empathy).

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Peculiarities : 3-MMC is known to cause a state of intense sexual arousal unrelated to any stimulation (you are aroused by the drug itself, regardless of the partner in front of you). As such, 3-MMC is widely used, often in combination with GBL (which once ingested becomes GHB) in chemsex practices (the use of certain psychoactive products in a sexual setting).

On the same subject ⋙ Investigation: Chemsex, the coming epidemic

⋙ “I tell my boyfriend that I would like us to try together” - Chemsex, the day it all started

⋙ Report: How to get out of chemsex: psycho, addict, sex... the difficult care of patients

PVP, MDPV, alpha, methylone and other "substituted cathinones"

Family : cathinones

While 3-MMC and 4-MMC are the main representatives of their family (cathinones, i.e. derivatives of khat), there are dozens of other products developed on the same basis and in line with mephedrone, such as Alpha-PHP, Alpha-PVP, methylone or even MDPV.

Other names: NRG1, 2 or 3, Top Cat, M Cat, subcoca-1. They are sometimes sold as "fertilizers or "research chemicals".

Effects : The effects are quite similar to other cathinones, but can vary greatly from one product to another. Thus, they increase the effects of dopamine, serotonin and norepinephrine and can cause euphoria, intensification of sensations, mental stimulation, improved empathy and sociability. They also have a powerful sexually arousing effect.

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Among the negative effects, there are among others anxiety, prolonged insomnia, aggressive behavior, suicidal thoughts, confusion, panic attacks... Cases of death have already been reported. Again, this is a very highly addictive molecule, and most substituted cathinones have stronger and more violent effects than mephedrone.

Methoxetamine (and ketamine)

Family : arylcyclohexylamines

Appeared in 2011, methoxetamine (MXE) is a very popular drug in the party scene. Dissociative and hallucinogenic drug (family of arylcyclohexylamines, yes it's hard to say), it creates a feeling of cocoon and calm, can cause visual hallucinations and a feeling of decorporation. It is used to find relaxation, euphoria and good humor. Ketamine is basically an anesthetic. Some produce hallucinogenic effects, others do not.

Other names : MXE, 3-MeO-2-Oxo-PCE, Mesket,

Effects : Methoxetamine has effects similar to those of ketamine, and is often sold under this name. However, it is not the same thing: its effects are much more powerful, but also more durable, which can lead to overdoses and therefore complications. It is very important not to consume it with other narcotics that act on serotonin (such as MDMA), otherwise you risk serotonin syndrome (confusion, delirium, agitation, tachycardia, hypertension, hyperthermia, neuromuscular problems... )

Synthetic cannabinoids

Family : cannabinoids

Do you find this joint particularly strong, compared to what you used to smoke in the past? This is normal: it may simply not be a natural substance. Synthetic cannabinoids are chemical molecules that mimic the effects of THC (the active ingredient in cannabis, which gives it its effect). In some countries, some of these products are legal, and they can easily be found on the internet as "high smoking herbal blends". They do not contain cannabis but produce the same effects when smoked. The vagueness surrounding their method of production makes it impossible to know how they are dosed, and it does not

Other names : Spice Gold, Spice Silver, Spice Diamond, Yucatan Fire, Incense, K2, Sence, Chill X, Smoke, Genie

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Effects: The effects are felt for 4 to 6 hours, but can last a whole day. They are similar to cannabis, but much stronger. Side effects can lead to depression, anxiety, agitation, paranoia as well as certain psychiatric complications. A few rare cases of death have been reported.

THC concentrates

Strictly speaking, THC concentrates are not new designer drugs. This is indeed real THC...extremely concentrated (yes, that was easy). We thus find leaves or oil concentrated at 70%, 80 or even 95%. Suffice to say that the effect can be extremely strong, not to say violent, and the side effects can be exacerbated (attacks of paranoia, palpitations, addiction, serious respiratory problems, etc.). If you see such concentrations, it is therefore modified cannabis, to be avoided!

Other names : BHO, shatter, wax, dabs, honey

Mescaline derivatives

Family: psychedelic phenethylamines

Mescaline is extracted from American cacti, of which Peyote is the best known representative. It is used in shamanic rituals, or for recreational purposes. In recent years, many chemical derivatives have been developed such as thiomescaline , escaline or proscalin , as well as the 2C-x family (see below).

Other names : mezcalin, mescalito, peyote, tmpea, mess, wizz,

Effects : Be careful, the trip can be long and last up to 10 and 12 hours with psychedelic hallucinations, time distortion, mystical visions, euphoria, and empathy.

On the same subject ⋙ Peyote : I ate the cactus with mescaline and I met an alien

⋙ Michel and Bernard: when we "treated" homos with LSD and mescaline in French psychiatric hospitals

The 2C-x (2C-B, 2C-I, 2C-T, etc.)

Family : psychedelic phenethylamines

The term 2C-x is used to refer to "psychedelic phenethylamines containing methoxy (O–CH3) groups found in the 2 and 5 position of the benzene ring". Say it like that, it might sound a bit fuzzy, but tell yourself that every time a drug starts with "2C", it's part of it (like 2C-B , the best known), and that's where also drugs seeking to reproduce the effects of mescaline, most of which were discovered in the 1970s and 1980s.

Other names : Fly (or 2C-B-Fly, be careful, it is a different molecule from 2C-B), Nexus, Eve or Venus (for 2C-B), 7h Heaven, Beautiful, Blue Mystic, Lucky 7, Tripstasy

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Effects: 2C-x have effects that last 4 to 6 hours (sometimes longer) and cause visual hallucinations, euphoria, shape distortion, heightened senses, a sense of well-being. It is also a stimulating product, sometimes causing sexual arousal. But they can also be responsible for delusional states, paranoia, depersonalization, disturbing hallucinations, or even confusion.

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